61 formulas · Fragrance-free · Made in the USA
Skincare that works
at the signal layer.
Neuroderm formulates around the pathways that tell skin how to behave — peptides, retinoids and barrier lipids at doses that are actually printed on the box. No fragrance, no filler percentages, no claims we cannot show you the study for.
Peptides
9
Smoother at 8 wks
92%
NS-01 · Bestseller
Synapse Repair Serum
Free shipping over $75
3–5 business days standard, tracked
30-day returns
Opened or unopened, no questions
Fragrance-free throughout
Cruelty-free · Vegan formulas
Encrypted checkout
256-bit SSL · PCI compliant
The range
Ten categories. Sixty-one formulas.
12 products
Serums & Concentrates
High-concentration leave-on treatments. The step that does the most work in a routine.
6 products
Moisturizers
Creams, gel-creams and fluids that seal the routine and hold hydration through the day.
7 products
Cleansers & Prep
Washes, milks, toners and mists that clear the surface without stripping it.
4 products
Eye & Lip
Formulas dosed for the thinnest skin on the face, where everything shows first.
9 products
Masks & Treatments
Weekly and targeted steps — resurfacing, masking, spot work and overnight recovery.
3 products
Daylight Defense
Broad-spectrum sunscreen you will actually wear every morning.
3 products
Body & Hand
The same formulation standard, scaled for everything below the jaw.
6 products
Devices & Tools
At-home devices and accessories that make the routine measurably easier to keep.
7 products
Regimens & Sets
Pre-built routines. Every set is priced below the sum of its individual products.
4 products
Discovery & Add-ons
Minis, travel sizes and samples for trying a formula before committing.
Most reordered
What people come back for
NS-01
Synapse Repair Serum
Nine-peptide overnight signal serum
30 ml / 1.0 fl oz
$89.95
NS-02
Axon Vitamin C 15%
Stabilised L-ascorbic brightening serum
30 ml / 1.0 fl oz
$70.00
NS-03
Relay Niacinamide 10%
Pore-refining tone serum
30 ml / 1.0 fl oz
$67.95
NS-04
Cortex Retinal 0.1%
Encapsulated retinaldehyde night serum
30 ml / 1.0 fl oz
$95.00
NS-07
Myelin Barrier Concentrate
Lipid-identical repair concentrate
30 ml / 1.0 fl oz
$84.95
NC-01
Reset Gel Cleanser
Daily pH-balanced gel wash
150 ml / 5.0 fl oz
$29.95
NC-05
Balance Essence Toner
Hydrating post-cleanse essence
200 ml / 6.7 fl oz
$50.00
NM-01
Baseline Daily Cream
Everyday moisturizer, all skin types
50 ml / 1.7 fl oz
$50.00
Why "neuro"
Skin is a signalling organ before it is a surface.
Most skincare is written as though the skin were a sponge — apply enough of something and it soaks in. It does not work like that. Skin is a densely innervated, constantly signalling organ, and the ingredients that change how it looks are the ones that participate in that signalling.
That is what peptides are: short chains that read as messages. It is why retinaldehyde outperforms retinol at a lower percentage, and why a ceramide, cholesterol and fatty-acid blend at 3:1:1 behaves differently from the same lipids in the wrong ratio. We formulate to the mechanism, then print the dose.
Read the formulation principlesDisclosed percentages
Every active concentration is printed on the product page and the carton. If a number is missing it is because the ingredient is below a level worth claiming — so we left it out instead.
One active, one job
We do not stack eleven headline actives into one bottle. Formulas that try to do everything at once do most of it badly and irritate on the way.
Tolerability is a result
78% of Cortex Retinal users complete twelve weeks without stopping. A retinoid you abandon in week three does nothing, however strong it is.
Packaging that protects
Airless pumps and opaque glass where the formula needs it. Vitamin C in a clear dropper bottle is a decision to sell you an orange liquid.
Start from the problem
What is your skin actually doing?
Pick the thing that bothers you most. We will show you the two or three formulas that address it — not the whole catalogue.
Fine lines & firmness
26Peptide and retinoid routes for the look of lines, laxity and loss of bounce.
See the formulasTone & dark spots
13Vitamin C, azelaic and tranexamic routes for uneven tone and the look of spots.
See the formulasRedness & sensitivity
19Low-irritant formulas for skin that flushes, stings or reacts easily.
See the formulasTexture & pores
16Gentle acids and enzymes for rough patches and the appearance of pores.
See the formulasDryness & barrier
30Ceramides, lipids and humectants for tightness, flaking and a compromised feel.
See the formulasBlemishes & congestion
11Clarifying formulas for breakouts, congestion and the marks they leave behind.
See the formulasBuy the routine, not the product
Pre-built regimens
Seven sets, each priced well below the sum of its parts and built so nothing in the box conflicts with anything else in it.
Verified purchases
41,000 reviews. 4.8 average.
“I have tried a lot of retinoids and quit all of them by week three. This is the first one I have used for six months straight. The ramp-up card in the set is the reason.”
Marguerite D.
Verified · The Firming System
“My skin was wrecked from over-exfoliating. The Barrier Rescue Kit tells you to stop doing things, which no brand does, and it worked in about ten days.”
Tomas R.
Verified · The Barrier Rescue Kit
“The SPF is the only one I have found that leaves genuinely no cast on deeper skin and does not pill under makeup. I have repurchased it four times.”
Adaeze N.
Verified · Invisible Fluid SPF 50
Free with every order
Not sure which formula? Add a free sample and find out first.
One free 5 ml sample with every order, no minimum. Or pick exactly which formula you want to try for $5 — worth doing before you buy 30 ml of a retinoid.